| Date | Home Team | Away Team | Stadium | |
|---|---|---|---|---|
| 3/6 7:00PM PST | LA Galaxy | Chicago Fire | at StubHub Center | Get Tickets! |
| 3/15 4:00PM PDT | Portland Timbers | LA Galaxy | at Providence Park | Get Tickets! |
| 3/21 7:30PM PDT | LA Galaxy | Houston Dynamo | at StubHub Center | Get Tickets! |
| 3/28 4:00PM PDT | D.C. United | LA Galaxy | at RFK Stadium | Get Tickets! |
| 4/4 | Vancouver Whitecaps FC | LA Galaxy | at BC Place | Get Tickets! |
| 4/12 4:00PM PDT | LA Galaxy | Seattle Sounders FC | at StubHub Center | Get Tickets! |
| 4/18 7:30PM PDT | LA Galaxy | Sporting Kansas City | at StubHub Center | Get Tickets! |
| 4/26 2:00PM PDT | New York Red Bulls | LA Galaxy | at Red Bull Arena | Get Tickets! |
| 5/2 7:30PM PDT | LA Galaxy | Colorado Rapids | at StubHub Center | Get Tickets! |
| 5/6 6:30PM PDT | Real Salt Lake | LA Galaxy | at Rio Tinto Stadium | Get Tickets! |
| 5/9 5:30PM PDT | FC Dallas | LA Galaxy | at Toyota Stadium | Get Tickets! |
| 5/17 2:00PM PDT | Orlando City SC | LA Galaxy | at Citrus Bowl | Get Tickets! |
| 5/22 7:30PM PDT | LA Galaxy | Houston Dynamo | at StubHub Center | Get Tickets! |
| 5/27 7:30PM PDT | LA Galaxy | Real Salt Lake | at StubHub Center | Get Tickets! |
| 5/31 4:00PM PDT | New England Revolution | LA Galaxy | at Gillette Stadium | Get Tickets! |
| 6/6 7:30PM PDT | LA Galaxy | Vancouver Whitecaps FC | at StubHub Center | Get Tickets! |
| 6/13 4:30PM PDT | Crew SC | LA Galaxy | at MAPFRE Stadium | Get Tickets! |
| 6/20 7:30PM PDT | LA Galaxy | Philadelphia Union | at StubHub Center | Get Tickets! |
| 6/24 8:00PM PDT | LA Galaxy | Portland Timbers | at StubHub Center | Get Tickets! |
| 6/27 7:30PM PDT | San Jose Earthquakes | LA Galaxy | at Stanford Stadium | Get Tickets! |
| 7/4 7:30PM PDT | LA Galaxy | Toronto FC | at StubHub Center | Get Tickets! |
| 7/17 8:00PM PDT | LA Galaxy | San Jose Earthquakes | at StubHub Center | Get Tickets! |
| 7/25 6:00PM PDT | Houston Dynamo | LA Galaxy | at BBVA Compass Stadium | Get Tickets! |
| 8/1 6:00PM PDT | Colorado Rapids | LA Galaxy | at Dick's Sporting Goods Park | Get Tickets! |
| 8/9 1:00PM PDT | LA Galaxy | Seattle Sounders FC | at StubHub Center | Get Tickets! |
| 8/15 6:00PM PDT | FC Dallas | LA Galaxy | at Toyota Stadium | Get Tickets! |
| 8/23 2:00PM PDT | LA Galaxy | New York City FC | at StubHub Center | Get Tickets! |
| 8/28 8:00PM PDT | San Jose Earthquakes | LA Galaxy | at Avaya Stadium | Get Tickets! |
| 9/12 7:30PM PDT | LA Galaxy | Montreal Impact | at StubHub Center | Get Tickets! |
| 9/19 6:30PM PDT | Real Salt Lake | LA Galaxy | at Rio Tinto Stadium | Get Tickets! |
| 9/26 7:30PM PDT | LA Galaxy | FC Dallas | at StubHub Center | Get Tickets! |
| 10/4 6:30PM PDT | Seattle Sounders FC | LA Galaxy | at CenturyLink Field | Get Tickets! |
| 10/18 4:00PM PDT | LA Galaxy | Portland Timbers | at StubHub Center | Get Tickets! |
| 10/25 4:00PM PDT | Sporting Kansas City | LA Galaxy | at Sporting Park | Get Tickets! |